I have no idea if this will help.
But I've noticed the following: Humans are NOT affected by this murderous urge bug.
But these random NPCs don't interact with ANYONE. For example, a monster won't attack the randomly generated hunter, and the hunter won't attack the monster. Furthermore, these random NPCs are unresponsive.
But as soon as I summon something and then attack the random NPC with it, the random NPC starts interacting and then attacks other monsters as well. Likewise, the monsters will then target him. Perhaps the problem lies there as well, that the rune isn't working? That would at least be my guess.
The Random Bandits are different. They're completely normal.
I'd like to help myself, as this is probably my last run. I love the Dark Mage and want to enjoy it with Ethernal Breeze ^^ So if any other information is available, I might be able to help.